What do you call a brilliant musician who also happens to have Down Syndrome?

Retarded.

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Happen Jokes More Happen Jokes

What happens when you throw a hand grenade into a kitchen?

Well, the mess is the same but the annoying jabbering stops.

What happens when a Pokemon goes through puberty?

It's bells sprout.

Syndrome Jokes More Syndrome Jokes

What is the syndrome that endangers the dental well-being of over-anxious or stressed-out LGBT's?

brucism

How do you tell if your eggs are rotten?

If your kid has down syndrome.