What do you call a brilliant musician who also happens to have Down Syndrome?

Retarded.

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What happens when you play the drums incorrectly?

You get repercussions

What happened on Reddit yesterday?

A pao-erful change

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What do you call a mentally handicapped System of a Down cover band?

Syndrome of a Down

What do you call a midget with Down Syndrome?

you call him a little slow